The present invention provides a method for destroying oxidase in cane juices. The method comprises the following steps: at a juice extraction stage of a sugar making process, CIO2 is added to cane juices juiced by each squeezer at the juice extraction stage or quasi delivered to osmotic water of the last-an M squeezer; oxidase in the cane juices are destroyed; M is any integer from 2 to 10; the cane juices juiced by each squeezer at the juice extraction stage include diluted cane juices quasi delivered to an N squeezer after being juiced by an N plus 1 squeezer; the value range of N is that N is any integer from 2 to 9; or the cane juices juiced by each squeezer at the juice extraction stage include a mixed cane juice mixed and formed by a cane juice juiced by a first squeezer and a cane juice juiced by a second squeezer after passing through a curved sieve. Compared with the prior art, the method has the beneficial effects that (1), the damage ratio of oxidase in the cane juices reaches more than 80 percent; (2), a sugar product has the advantages of low color value, low sulphur content, improved purity and high quality; (3), no sucrose loss is caused; and (4), the method has the advantages of simple process and low cost.