The invention discloses a method and a device for reducing the interferences of an indoor base station. The method of the invention comprises the following steps: when user equipment (UE) has service connection, related information of current location of the UE is obtained; when the current location information of the UE falls within the threshold value range of the coverage area of the indoor base station corresponding to the preserved UE, the indoor base station is indicated to start a wireless transmission unit; and the UE resided in a cell of a public mobile communication is switched to the cell of the indoor base station. By adopting the method and the corresponding equipment, the interferences on other HNB can be reduced greatly, and then the interferences of the overall system are reduced. In addition, the wireless transmitting element of HNB is usually under a closed state, so that the power consumption of HNB is reduced; and meanwhile, the radiation is reduced, and HNB is ensured to be an environment healthy indoor wireless device.