The proposal for eliminating inter-cell interference based on cooperation with the prior base station has problems such as resources occupation and Backhaul load increment. The invention provides a multi-base station cooperative multiple-input multiple-output (MIMO) with low information interaction in a wireless network and a scheduling method and a device thereof. The scheduling method comprises: a base station acquires information relevant to signal quality between the base station and each mobile terminal and reports to a scheduling device, wherein the reported signal quality relevant information is preferably a relative signal strength indicator (RSSI) or a channel quality indicator (CQI) with small data size; the scheduling device selects a service base station for each mobile terminal and determines a specific base station to eliminate the interference from a specific mobile terminal; and the scheduling device further controls to correspondingly transmit service data of the mobile terminal to the service base station; the base station determines the serviced terminal and the terminal of which the interference is eliminated. When servicing the mobile terminal on a time-frequency resource and eliminating the interference from other base stations, the base station only needs to acquire channel state information of the mobile terminal associated with the base station to the base station on the corresponding time-frequency resource and calculate a pre-coded matrix, so as to pre-code mobile terminal service data from the service base station and generate downlink signals to be transmitted; and the process is independently carried out in various base stations.