The invention belongs to the technical field of medicine, in particular relates to a cephalosporin ramification containing pyrazolo triazine iodonium, the salt acceptable in medicine thereof, an ester easily hydrolytic thereof, a hydrate thereof and a hydrate of the salt or ester thereof which are shown in a general formula (I), wherein, R[1], R[2], R[3], R[4] and X are defined in an instruction;moreover, the invention also relates a preparation method of the compounds, medicine composites containing the compounds as well as the applications of the compounds used in the medicines for curing and/or preventing infectious diseases.