The present invention providing a Chinese medicine ointment, particularly the one for curing herpes zoster and the preparation thereof, is directed to a drug combination of antibiotic and antiviral drug with the following disadvantages: a slow effect, an easy entry to the outbreak period, a long treatment time, a high cost of treatment and the like. The ointment with hedgehog skin and sesame oil as raw materials has properties in a simple prescription and production, a low cost, healing fast and a high cure rate without toxic and side effect.