The invention relates to a medicine for curing cardio-cerebral diseases, which belongs to the technical field of medicine. The weight of active compositons is that zizyphus vulgaris 160-250 parts, cinnamon 150-210 parts, poria alba 100-200 parts, shizandra 180-230 parts, ustulation keel 180-350 parts, rehmanniae praeparatum 300-650 parts, platycladi seed 160-250 parts, sodium succinate 100-220 parts, salvia miltiorrhiza bge 300-700 parts, grassleaf sweelflag rhizome 280-360 parts, angelica 150-310 parts, radix polygalae 280-350 parts, root of pseudo-ginseng 280-350 parts, YanHuSuo 280-350 parts, carthamus tinctorius L 180-300 parts, mature aconite 180-300 parts, radix curcumae 100-300 parts, lucid ganoderma 300-650 parts, pubescent holly root 100-800 parts, common burreed rhizome 250-300 parts, zedoary 180-300 parts, scrophularia 180-300 parts, agaric 260-350 parts, szechuan lovage rhizome 500-700 parts, sanguisuga 180-350 parts, sun euphorbia herb 180-360 parts, ginseng 180-360 parts, gadfly 180-360 parts, and radix astragali 180-360 parts. The invention is capable of dilateing coronary arteries, reducing myocardial oxygen consumption, increasing coronary blood flow, strengthening the myocardium function, decreasing blood-fat and blood-pressure, inhibiting platelet aggregation, delaying angiosclerosis, eliminating free-radicals, facilitating thromboclasis, reducing vascular resistance and the ischemic area, preventing endothelium from damage, increasing cerebral blood flow, and removing vasospasm, thereby the function of protecting the brain tissue cells is achieved.