The present invention relates to the industrial dust removal technical field and especially is an efficient wear-resistant drum cyclone dust remover, which is applicable to a first-order dust removal of large equipments such as a blast furnace etc. the dust remover includes an air inlet pipe, a vent pipe, an ash collecting bucket, a cyclone separating room, an airflow distributing room and an airflow-limiting and dust-restraining device. The dust remover is characterized in that a central airflow distributing cone is arranged inside the airflow distributing room; the cyclone separating room consists of an inner room and an outer room; the side wall of the inner room is porous type side wall, and the sides of the pores are provided with wear-resistant upwind blocks. The bottom of the outerroom forms the ash collecting bucket. 6 to 10 vertical cyclone square tubes are arranged at the upside inside the cyclone separating room, and the upper tube openings are provided with upwind plates and downwind plates. The bottom of the cyclone separating room is connected with an oblique cyclone square tube and a two-section type exhaust duct. The dust removal efficiency of the dust remover is high; a wearing degree of dust towards equipments is lower; the airflow flows smoothly inside the dust remover, and the safe performance of the whole dust remover is good.