A washing machine with an obliquely arranged wave wheel comprises a case body, a washing barrel arranged in the case body, a driving device arranged at the bottom of the washing barrel and a wave wheel arranged at the interior of the bottom of the washing barrel, wherein the input end of the wave wheel connects with the output end of the driving device; the surface of the wave wheel parallels with the bottom surface of the washing barrel; the bottom surface of the washing barrel and the horizontal bottom surface of the case body include an angle alpha; the wave wheel is a large wave wheel, the diameter of which is 75percent-95percent of the width of the washing barrel, or the area of which is 75percent-95percent of that of the washing barrel. The washing machine of the present invention has the advantages of excellent over-turning effect, uniform washing performance and higher cleanness ratio. The wave wheel of the washing machine is obliquely arranged, so the gravity center of the washing machine mitigates off the central position, and the forces exerted to the driving system by water and clothes are decomposed, thereby increasing the reliability in trouble-free working times andtime of the system; in addition, the washing machine lowers the water consumption and, with more significant water-saving effect, is suitable, in particular, for washing clothes in a low quantity.